Brindley proposed that we initially generate movements , under higher cerebral control. As the movement is practiced, the cerebellum learns to link within itself the context in which the movement is made to the lower level movement generators. Marr and Albus proposed that the linkage is established by a special input from the inferior olive, which plays upon an input-output element within the cerebellum during the period of the learning. When the linkage is complete, the occurrence of the context (represented (...) by a certain input to the cerebellum) will trigger (through the cerebellum) the appropriate motor response. The movement is distinguished from the conscious movement by its now being automatic, rapid, and stereotyped. The idea is still controversial, but has been supported by a variety of animal studies and, as reviewed here, is consistent with the results of a number of human PET and ablation studies. I have added to the idea of context-response linkage what I think is another important variable: novel combinations of downstream elements. With regard to the motor system and the muscles, this could explain how varied combinations of muscles may become active in precise time-amplitude specifications so as to produce coordinated movements appropriate to specific contexts. In this target article, I have further extended this idea to the premotor parts of the brain and their role in cognition. These areas receive influences from the cerebellum; they are active both in planning movements that are to be executed and in thinking about movements that are not to be executed. From recent evidence, the cerebellar output extends even to what has been characterized as the ultimate frontal planning area, the cortex, area 46. The cerebellum thus may be involved in context-response linkage, and response combination even at these higher levels. The implication would be that, through practice, an experiential context would automatically evoke a certain mental action plan. The plan would be in the realm of thought, and could lead to execution. The specific cerebellar contribution would be one of the context linkage and the shaping of the response, through trial and error learning. The prefrontal and premotor areas could still plan without the help of the cerebellum, but not so automatically, rapidly, stereotypically, so precisely linked to context, or so free of error. Nor would their activities improve optimally with mental practice. (shrink)

The concept of entropy in nonequilibrium macroscopic systems is investigated in the light of an extended equation of motion for the density matrix obtained in a previous study. It is found that a time-dependent information entropy can be defined unambiguously, but it is the time derivative or entropy production that governs ongoing processes in these systems. The differences in physical interpretation and thermodynamic role of entropy in equilibrium and nonequilibrium systems is emphasized and the observable aspects of entropy production are (...) noted. A basis for nonequilibrium thermodynamics is also outlined. (shrink)

I Think there is scarcely any academic subject regarding which there exists so much general misapprehension as philosophy. If I were to introduce myself to the readers of almost any newspaper as a professor of chemistry, or of classics, or of music, most of them would have a fairly good general idea of the nature of my subject. But if I were to introduce myself as a professor of philosophy, I suspect that many of them would vaguely associate my subject (...) with theosophy, or palmistry, or occultism. Very few would have any notion of what philosophy really is. Even in a university, even among the learned themselves, it would be true to say, I think, that. (shrink)

We are familiar with the statement that the present world-conflagration is, or involves, a struggle between two different philosophies. Obviously the statement is very vague, and it is exceedingly difficult to say exactly what it means. But if it has any meaning at all, a professional philosopher ought to be supremely interested in it. Philosophers are too apt to sit in their ivory towers, weaving curious distinctions and debating strange intellectual puzzles, without any consideration of their implications for humanity. For (...) even the most abstract questions invariably have, in the end, important practical bearings. And we are apt to forget that, in the last analysis, philosophers are the uncrowned rulers of the world. For their ideas, secretly infiltrating among the masses, are among the forces which drive civilizations. Plato has had more influence on the destiny of man than the inventor of the steam engine. And so I make no apology for attempting to discuss here the question whether the two great nations now engaged in war, Germany and Britain, represent any philosophical ideas, what the philosophical issues of the war are, and where, in those issues, the truth, or the greater degree of truth, lies. And the paper will have two parts. In the first I shall try briefly to state what I believe the issues to be. In the second I shall attempt to discover whether there is any rational ground for preferring the philosophy of the one side to that of the other. (shrink)

I contend that Jews, Christians, and Muslims who seek peace should not be reluctant to acknowledge the existence of their sometimes profound disagreements, or to affirm the truth of their own beliefs and practices. Since this places me at odds with John Hick, I analyze his views, granting the strengths of his critical realism and arguing that his revisionist-pluralist theory of religion has significant limitations for interreligious dialogue. Since the veridical-pluralist alternative I propose facilitates rather than stifles disagreement, I examine (...) three different conceptions of dialogue that acknowledge the importance of disputes among those searching for truth. I also discuss three virtues--honesty, empathy, and humility--whose cultivation would make us less likely to fail in our search for truth and the peace that is its sign and fruit. (shrink)